Introduction

Fresh Blood Imaging (FBI) is a non-contrast MR angiography technique that uses the patient’s own blood as a contrast agent, eliminating the need for gadolinium-based contrast media. This technique is particularly useful for patients with renal insufficiency who are at risk of developing Nephrogenic Systemic Fibrosis (NSF).

Principle and Technique

FBI uses a 3D ECG-gated sequence to acquire data during systole and diastole. The technique suppresses signal from stationary anatomy and produces bright blood angiograms with minimal venous and background signals. It allows for large anatomical coverage and can be used to image the aorta and major runoff vessels.

Applications and Benefits

FBI has various applications, including peripheral runoff and renal MRA exams. It offers several benefits, including the elimination of contrast agent costs, reduced risk of NSF, and improved patient safety. Additionally, FBI can be used to evaluate patients with severe vascular disease.

Practical Tips and Clinical Cases

Practical tips for running an FBI exam include ensuring patient comfort, choosing the appropriate dephasing gradient strength, and tailoring the exam for unilateral disease. Clinical cases demonstrate the effectiveness of FBI in evaluating severe vascular disease and comparing favorably with invasive X-ray Digital Subtraction Angiography (DSA).

Manual:

Download: Fresh Blood Imaging: Setting the Standard for Non-Contrast Peripheral MR Angiography

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